Under active development. Data is being added and corrected on an hourly basis.

← Back to Peptides
Retatrutide structure

Retatrutide

Metabolic
Phase 2 Research
40%
Low-Moderate Risk
2/5

Also Known As

LY3437943 · Triple G

Overview

Retatrutide is a novel triple incretin agonist in clinical trials. Targets GIP, GLP-1, and glucagon receptors for enhanced metabolic effects.

Mechanism of Action

Activates GIP, GLP-1, and glucagon receptors simultaneously. The glucagon component may enhance energy expenditure and fat oxidation.

Quick Reference

Common Dose 1mg-12mg
Frequency Once weekly
Half-Life ~6 days
Storage Refrigerate.

Notes

Currently in Phase 3 trials. Shows greater weight loss than dual agonists in studies.