Also Known As
Human Chorionic Gonadotropin · Pregnyl · Novarel · Ovidrel
Overview
HCG is a glycoprotein hormone produced during pregnancy. In males, it mimics luteinizing hormone (LH), stimulating Leydig cells to produce testosterone and maintain testicular size.
Mechanism of Action
Binds to LH receptors on Leydig cells, stimulating intratesticular testosterone production and maintaining spermatogenesis when exogenous testosterone suppresses the HPTA.
Quick Reference
Common Dose 250-500 IU
Frequency 2-3x weekly
Half-Life 24-36 hours
Storage Refrigerate after reconstitution. Lyophilized stable at room temp.
Notes
Essential for TRT to prevent testicular atrophy and maintain fertility. Also used for PCT.