Also Known As
Acadesine · AICA-Riboside · ZMP precursor
Overview
AICAR (5-aminoimidazole-4-carboxamide ribonucleoside) is a cell-permeable AMPK activator. Converted intracellularly to ZMP which mimics AMP. Research focuses on exercise mimetic effects, metabolic regulation, and cancer.
Mechanism of Action
Taken up by adenosine transporters, phosphorylated to ZMP. Activates AMPK by binding gamma subunit. Stimulates glucose uptake, fatty acid oxidation, and mitochondrial biogenesis.
Quick Reference
Notes
Poor oral bioavailability (<5%). Does not cross BBB efficiently. Short intracellular half-life. Research compound - WADA prohibited.
Dosing Protocol
Pharmacokinetics
Administration
Reconstitution
Special Instructions
Exercise mimetic - inject 30-60 min before training. Poor oral bioavailability (<5%) requires injection. Does not cross blood-brain barrier efficiently. WADA prohibited.
Warnings
Contraindications
Drug Interactions
Possible Side Effects
Legal & Regulatory
Pregnancy
Molecular Data
No sources available yet.
Related Peptides
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