Also Known As
ONO-7643 · Adlumiz
Overview
Anamorelin is a non-peptide, orally active ghrelin receptor agonist. Approved in Japan for cancer cachexia. Stimulates appetite, increases lean body mass, and promotes GH release.
Mechanism of Action
Selective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR). Centrally penetrant. Increases GH, IGF-1, and appetite.
Quick Reference
Notes
Approved in Japan for cancer anorexia-cachexia. Not FDA approved. Metabolized by CYP3A4.
Dosing Protocol
Pharmacokinetics
Administration
Special Instructions
Take on empty stomach 1 hour before first meal. Approved in Japan for cancer cachexia. CYP3A4 interactions possible.
Warnings
Contraindications
Drug Interactions
Possible Side Effects
Legal & Regulatory
Pregnancy
Molecular Data
No sources available yet.