Under active development. Data is being added and corrected on an hourly basis.

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MK-677 structure

MK-677

Growth Hormone
Phase 3 Research
60%
Low-Moderate Risk
2/5

Also Known As

Ibutamoren · Ibutamoren Mesylate · L-163,191 · Nutrobal

Overview

MK-677 is a non-peptide ghrelin receptor agonist that can be taken orally. Increases GH and IGF-1 levels for 24 hours after single dose.

Mechanism of Action

Mimics ghrelin signaling at the GHSR receptor. Increases GH pulsatility and elevates IGF-1 without affecting cortisol.

Quick Reference

Common Dose 10-25mg
Frequency 1x daily (oral)
Half-Life ~24 hours
Storage Store at room temperature. Oral administration.

Notes

Not technically a peptide but often grouped with GH secretagogues. May increase appetite and water retention.