Under active development. Data is being added and corrected on an hourly basis.

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IGF-1 LR3

Growth Hormone
Phase 1 Research
35%
Moderate Risk
3/5

Also Known As

Long R3 IGF-1 · Long Arginine 3-IGF-1 · LR3-IGF-1

Overview

IGF-1 LR3 is an 83 amino acid synthetic analog of IGF-1 with an arginine substitution at position 3 and 13 additional N-terminal amino acids. These modifications reduce IGFBP binding and extend half-life to 20-30 hours, making it approximately 3x more potent than native IGF-1.

Mechanism of Action

Binds IGF-1 receptor with high affinity. Reduced binding to IGFBPs increases free circulating levels. Promotes protein synthesis, glucose uptake, and cell proliferation.

Quick Reference

Common Dose 20-60mcg
Frequency 1x daily (subq or IM)
Half-Life ~20-30 hours
Storage Refrigerate reconstituted. Sensitive to degradation.

Notes

Approximately 3x more potent than native IGF-1. Used for muscle growth and recovery research. Site injections common.