Dosing Protocol
Typical Dose 250 mcg
Range 100 - 500 mcg
Loading Phase 250 mcg × 21 days
Maintenance 500 mcg weekly
Pharmacokinetics
Half-Life 1.0 hrs
Onset 15 min
Peak 1.0 hrs
Duration 3.0 hrs
Bioavailability 95%
Primary Route Subcutaneous
Administration
Routes Subcutaneous, Nasal
Injection Sites Abdomen, Thigh
Needle Gauge 29-31G
Syringe Type Insulin
Timing Evening, before sun exposure
Reconstitution
Diluent Bacteriostatic Water
Volume 2 mL
Concentration 5000 mcg/mL
Stability 30 days refrigerated
Vial Sizes 10 mg
Special Instructions
Loading: 250-500mcg daily for 2-3 weeks with UV exposure. Maintenance: 500mcg once weekly. Start very low (100mcg) to assess tolerance.