Also Known As
Mitochondrial ORF of the 12S rRNA Type-C
Overview
MOTS-c is a 16 amino acid peptide encoded by the mitochondrial genome. Regulates metabolic homeostasis, glucose metabolism, and insulin sensitivity. Activates AMPK pathway.
Mechanism of Action
Activates AMP-activated protein kinase (AMPK), enhancing glucose uptake and fatty acid oxidation. Regulates the folate-methionine cycle.
Quick Reference
Notes
Experimental peptide. Prohibited by WADA as AMPK activator. No completed human clinical trials.
Dosing Protocol
Pharmacokinetics
Administration
Reconstitution
Special Instructions
HIGHLY UNSTABLE - degrades 85-90% in 2-3 hours at room temp. Keep frozen until use. Reconstitute immediately before injection.
Warnings
Contraindications
Drug Interactions
Possible Side Effects
Legal & Regulatory
Pregnancy
Molecular Data
No sources available yet.