Under active development. Data is being added and corrected on an hourly basis.

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Tabimorelin structure

Tabimorelin

Growth Hormone
Phase 2 Research
50%
Moderate Risk
3/5

Also Known As

NN703 · NN-703

Overview

Tabimorelin is an orally active ghrelin receptor agonist that stimulates growth hormone release. Developed by Novo Nordisk but discontinued after Phase II trials due to CYP3A4 inhibition concerns.

Mechanism of Action

Potent agonist of the ghrelin/growth hormone secretagogue receptor (GHSR). Oral bioavailability ~30%. Mechanism-based inhibitor of CYP3A4.

Quick Reference

Common Dose 10-20mg
Frequency 1x daily (oral)
Half-Life ~4 hours
Storage Store at room temperature. Oral formulation.

Notes

Development discontinued due to CYP3A4 inhibition. May cause drug interactions. Research compound only.